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   CALee Acupuncture Age-Related Diabetes — Part 4 How Does Modern Research Evaluate This Formula? In the previous parts of this series, we explored how Liuwei Dihuang Wan was designed not to lower blood sugar directly, but to replenish a depleted Yin foundation , regulate internal heat , and restore metabolic balance . How, then, does modern research evaluate such a formula? What Clinical Studies Report A number of clinical studies have suggested that Liuwei Dihuang Wan may influence markers associated with glucose regulation in patients with Type 2 diabetes . Several studies have reported that when Liuwei Dihuang Wan is added to conventional diabetes medications, improvements in: fasting blood glucose HbA1c appear greater than with medication alone (Zhang et al., 2013). Some studies have also reported changes in HOMA-IR , a commonly used measure of insulin resistance . Research on Diabetic Complications Studies have also examined the formula in relation ...

  CALee Acupuncture Age-Related Diabetes — Part 3 Liuwei Dihuang Wan : A Formula for the Depleting Body In Part 2, we explored how Classical Medicine views age-related diabetes as a process in which the body’s Yin foundation gradually becomes depleted, leading to increasing internal heat and disruption of fluid regulation. From this perspective, how is a treatment formula constructed? A Formula Built Around Restoration and Balance Liuwei Dihuang Wan is one of the most representative formulas reflecting this treatment principle. First recorded during the Song dynasty in Xiao Er Yao Zheng Zhi Jue , it has been used for centuries as a foundational formula for nourishing Kidney Yin (Bensky et al., 2004). Composition of the Formula Liuwei Dihuang Wan consists of six herbs: Rehmanniae Radix Preparata ( Shudihuang ) Corni Fructus ( Shanzhuyu ) Dioscoreae Rhizoma ( Shanyao ) Alismatis Rhizoma ( Zexie ) Moutan Cortex ( Mudanpi ) Poria ( Fuling ) These six herbs are ...

CALee Acupuncture Age-Related Diabetes — Part 2 Classical Medicine does not measure blood sugar. So what does it observe? In Part 1, we explored how modern medicine understands age-related diabetes as a condition shaped by: insulin resistance declining beta-cell function chronic inflammation Yet in clinical practice, all of these complexities ultimately converge into a single target: a number. Classical Medicine does not measure that number. So how did Classical Medicine understand conditions resembling diabetes long before blood glucose testing existed? Xiaoke — The Slowly Wasting Body In Classical Medicine literature, conditions resembling diabetes were described centuries ago under the term: Xiaoke (消渴) Xiao (消) refers to gradual depletion or wasting Ke (渴) refers to persistent thirst Descriptions of excessive thirst and fluid depletion appear even in the Huangdi Neijing , with later medical texts expanding the concept in greater detail (Unschuld, 2011). If modern ...

   CALee Acupuncture Age-Related Diabetes — Part 1 When blood sugar returns to normal, has the person truly become healthy? Globally, approximately 25–30% of adults over the age of 65 are diagnosed with diabetes. A fasting blood glucose level above 126 mg/dL, or an HbA1c above 6.5%, meets the criteria for Type 2 diabetes . The moment the numbers cross that threshold, you become a patient— and blood sugar management begins ( American Diabetes Association, 2023 ). Modern medicine justifies these criteria through decades of epidemiological research. Persistently elevated blood glucose damages blood vessels and contributes to complications affecting: the kidneys eyes nerves cardiovascular system The numbers do not lie. But age-related diabetes tells a slightly different story. Why Does Aging Disrupt Blood Sugar Regulation? As aging progresses, the body’s glucose regulation system changes in multiple ways simultaneously. Increasing Insulin Resistance One of the earl...